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Genomics is Applied Genetics

In the study of humans migration, genomics and genetics really mean the same thing. Genetics is applied by genomics which analyses the structure of genomes. As well as migration much light has been shed on the origin of certain diseases.
The evolution of man humans
Alcoholism has evolved in man because it was useful as a curative agent. It first occurred naturally from stored grain. Beer jugs were found with Stone Age people. Because it came from collected grains, alcohol and bread probably came into human culture at the same time, Alcoholism is a side effect of evolution. Benefits for Man outweighed this issue and anyway it could have started commerce via trade in beverages.

Having a particular gene predisposes groups of humans to sickle cell disease. It was said to be a disease of black gene pools. However, white people can develop the condition if they have the gene. 

There is a predisposition gene for type 2 diabetes, though this malady can be caused by diet and taking medications over a Long period.  Other gene related diseases include: Parkinson's, irritable bowel, prostate cancer, cystic fibrosis, autism (questionable) and so on.

Contrary to the mistaken view put forward by some scientists who should know better, humans never mated with Neanderthals. Each had a different number of chromosome so fertile offspring were not possible (see: Britannica).
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