Adventure Ausrama Blog

Scientists have found a way of transforming ordinary sugar into hydrocodone. This will lead to a cheaper way of manufacturing opiates. Unfortunately, it will also make things easier for drug traffickers selling a cheaper product, Yeast changes sugar into pain killer. This takes out the entire one year growing season for poppies and the factory process itself. At present, 4,400 gallons of yeast is needed to produce a small amount of hydrocodone. Work will proceed to improve this. With yeast as the catalyst, it looks like plant-based medication manufacturing is under threat. Yeast has snippets of DNA added to reprogram cells into target compounds. Notably, a third of the world's supply of the medication artemisinin is already produced from modified yeast. Artemisinin needs six genes while hydrocodone requires 23. Some genes from rats arehydrocodone. put into the yeast to make A "halfway-house" way of manufacturing pain killers is possible. A strain ...

There is a new drug for malaria called artemisinin. It will be synthesized in a chemical process and the procedure is "green". The French pharmaceutical company Sanofi   produces a third of the world's demand annually. Unfortunately, the synthetic drug is expensive. Click to enlarge. Most of artemisinin is extracted from sweet wormwood. This is simple but the synthetic version involves the conversion of glucose into artemisinic acid: then three oxygen atoms are bonded on to produce artimsinin. It is complex. The use of toxic dichloromethane is not used in the new process. It was discovered, ironically, that water greatly assists the synthesis. It packs molecules together. Water-soluble photocatalyst is indeed clean and green. The result is a product that is purer than artemisinin taken directly from wormwood. ✴ Chemistry by Ty Buchanan ✴ http://www.adventure--australia.blogspot.com/ http://www.tysaustralia.blogspot.com/ http://adventure--austr...